In collaboration with the Poultry Association, Qimei Su’s antioxidant-based healthy farming program is gaining prominence.

On December 12, 2024, along the banks of the Zhangjiang River, amid the rich fragrance of narcissus flowers and a thriving poultry industry, the annual conference of the Zhangzhou Poultry Association was successfully held at the Xiangjiang Hotel. More than 200 professionals from related fields attended, including leaders from regulatory authorities, industry experts, representatives from poultry farms, and manufacturers such as Xinzhengyang and New Hope. As a global provider of acidification solutions, Guangdong nuacid Biotechnology Co., Ltd. received a special invitation from the Zhangzhou City Poultry Association to co-organize the event. nuacid showcased its two flagship products, “Fusuanbao” and “Qimeisu,” at the exhibition booth. Meanwhile, teachers Wen and E from the nuacid Innovation Center patiently and thoroughly addressed customers’ questions on health and nutrition in poultry farming, attracting considerable attention and favor from numerous farmers, technical personnel, and distributors.

At the event, Director Chen of the Zhangzhou Municipal Bureau of Agriculture and Rural Affairs delivered the opening address. He provided a concise analysis of current demand trends in the animal protein food market, noting that growing demand for high-quality foods presents unprecedented development opportunities for the poultry industry. However, he emphasized that only through continuous technological innovation and management optimization can the poultry sector achieve sustainable growth amid intense market competition. President Yang presented the 2024 work report, underscoring the importance of fostering mutual support and win-win outcomes within the industry through resource sharing, information exchange, and technical collaboration. He encouraged embracing new technologies and concepts to enhance industry competitiveness and deliver higher‑quality products and services to consumers.

The conference featured engaging presentations on topics such as “Summary of MS Prevention and Control Practices and Data Sharing in Large-Scale Laying Hen Farms,” “The Value of Breeding Stock,” “Analysis and Prevention of Egg Production Abnormalities in Laying Hens,” “Key Environmental Control Strategies for Autumn and Winter,” and “Oxytetracycline Process Innovation and Its Application in Poultry Production.” During the interactive salon session, Chairman Zheng Yang’s nutrition expert Lin Dengfeng and association board member and veterinary expert Huang KunSong were invited to discuss industry‑wide focal issues. Below are highlights from the event.

Topic 1: During the young pullet stage, should nutritional input be increased to extend the peak laying period? Teacher Huang believes that many farmers currently focus heavily on the beginning and end of production while neglecting the critical phase from chick rearing through pre-laying. This period is crucial for the development of the oviduct and ovaries, as well as for skeletal growth, yet it also experiences considerable stress. Therefore, this stage deserves greater attention. Chairman Lin argues that the growing period is pivotal for layer development; farmers should avoid cutting costs by purchasing low-quality ingredients or stockpiling large quantities to save money, as improper storage can lead to the formation of vomitoxin, T-2 toxin, and aflatoxin, causing poisoning in laying hens. Topic 2: Regarding water intake in 1–5-day-old chicks available on the market, how should drinkers be selected? Teacher Huang notes that most modern operations are large-scale, making manual watering with buckets inefficient; automatic cup drinkers and nipple systems are generally recommended. When using nipple drinkers, water pressure should be adjusted so that only a single drop emerges from each nipple, while ambient lighting should be brightened to ensure chicks can easily locate the water source. Chairman Lin emphasizes that water is paramount for life, making proper hydration essential; good water management ensures animal health. He recommends adding acidifiers to drinking water, which not only enhance digestion but also inhibit the proliferation of pathogenic microorganisms in water lines. Topic 3: In production, fatty liver disease frequently impacts chicken health and economics—how can it be addressed? Chairman Lin points out that fatty liver is a common issue in the late laying phase of layers, associated with high mortality, stemming from management practices, nutrition, and oxidative stress. Effective prevention involves maintaining a balance between energy and protein, supplemented early on with appropriate levels of calcium, 1,25-dihydroxyvitamin D3, and antioxidants (such as VE, VC, and endogenous antioxidants like superoxide dismutase).

An increasing number of livestock and poultry farming enterprises are recognizing the harm caused by stress and oxidative damage, as well as the associated economic losses. For years, nuacid NIC’s R&D experts have focused on stress resistance and antioxidant solutions, aiming to provide cost-effective strategies for farmers. As a pioneer in the animal feed industry, nuacid NIC has introduced molecular simulation and molecular docking technologies, employing specifically screened and structurally modified Lewis acids (such as daidzein) to develop “Qimeisu,” an antioxidant with highly active ingredients. Following patent‑protected activity enhancement, this product significantly boosts the expression of superoxide dismutase (SOD), the body’s primary defense against free radicals. Its benefits include: first, directly scavenging ROS and other free radicals to halt chain reactions; second, binding to the active site of the Keap1 protein to activate the Nrf2‑Keap1‑ARE signaling pathway, thereby markedly increasing the activity of downstream antioxidant enzymes like SOD, CAT, and GSH. This reduces oxidative damage and inflammatory responses caused by reactive oxygen species (ROS) in livestock and poultry, improving both production and reproductive performance. Studies conducted with Jiangxi Agricultural University (2023, 2024) demonstrate that adding Qimeisu during peak laying periods increases egg production by 2–4%, while late‑stage supplementation raises egg yield by 4–6% and extends egg shelf life by 3–7 days.

Although the event has concluded, new ideas and findings continue to resonate with attendees. Addressing participants’ concerns, Guangdong Suan Dongli’s NIC team notes that both high production levels and high conversion rates increase metabolic stress in poultry, naturally leading to greater generation of free radicals. Meanwhile, mycotoxins, elevated ammonia concentrations, inflammation, and disease—common challenges for livestock producers—also contribute to free radical formation. As potent oxidants, free radicals excel at stealing electrons. When an electron is taken, the targeted atom or molecule instantly becomes a free radical itself, triggering a chain reaction that spirals into a vicious cycle. Undoubtedly, oxidative stress can only be mitigated by pairing electrons, providing stable orbitals, or neutralizing free radicals to slow their attack on cell membranes. The latter approach involves identifying suitable endogenous antioxidants—substances that bind electrons—which broadly falls under the category of acids, specifically Lewis acids. As a leading developer and manufacturer of acid-based formulations, nuacid has pioneered the application of Lewis acid–base theory to acid formulation R&D, establishing a scientifically grounded pathway for developing Lewis-acid-based products that quench free radicals. In collaboration with renowned universities such as Sichuan Agricultural University, South China Agricultural University, and Jiangxi Agricultural University, nuacid has developed a next-generation endogenous antioxidant—Qimei Su—which significantly boosts superoxide dismutase expression in vivo and markedly improves growth and reproductive performance impaired by oxidative stress. Through this conference, NIC is confident that Qimei Su will provide a powerful new tool for promoting healthy poultry farming practices in Zhangzhou.

Written by: E Xiaodi

Review: Hu Youjun